ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (5): 899-908.doi: 10.11843/j.issn.0366-6964.2016.05.006

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Population Structure Analysis of Chinese Indigenous Sheep by 50K Chip Data

YUAN Ze-hu,WANG Hui-hua,HU Shi-jin,ZHU Cai-ye,ZHAO Fu-ping*,ZHANG Li,DU Li-xin,WEI Cai-hong*   

  1. (Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China)
  • Received:2015-07-01 Online:2016-05-23 Published:2016-05-23

Abstract:

The study aimed to construct the fine-scale profile for population structure of Chinese indigenous sheep breeds,which would provide the basis for the conservation and utilization of germplasm of sheep.NETVIEW,PCA,STRUCTURE and NJ tree were used to analyze the Illumina Ovine SNP 50K chip data from 11 sheep breeds (resources) including Ujumqin sheep,Hu sheep,Tong sheep,Large Tailed Han sheep,Lop sheep,Kazakh sheep,Duolang sheep,Diqing sheep,Tibetan sheep from Qinghai,Tibetan sheep from Sichuan and Tibetan from Tibet.The results showed the indirect genetic relationship between Lop sheep and Ujumqin sheep and the direct genetic relationship between Ujumqin sheep and all Mongolia group sheep breeds except for Lop sheep.Lop sheep and Kazakh group sheep breeds had closer genetic relationship,Kazakh sheep and Duolang sheep existed a certain degree of differentiation.Diqing sheep could separate from Tibetan group.Tibetan sheep from Tibet could separate from the other regions of the Tibetan sheep,Tibetan sheep from Qinghai and Sichuan couldn’t be separated.The results suggest that NETVIEW calculate efficiently and can reflect basic historical facts,thus it can be used as the tool for population structure analysis in the future;Ujumqin sheep is one of the oldest breeds of Mongolia group sheep breeds in this experiment;Lop sheep and other breeds from Xinjiang cluster together due to mixed lineage;There exist differentiation tendency in different regions of Tibetan sheep,but the differentiation is not serious.

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